Preheat oven to 350°F.
Line a 9 x 5 inch pan with parchment paper.
In a large bowl, stir together eggs, minced garlic, worcestershire sauce, water, salt, pepper, onion powder, red pepper flakes, and thousand island dressing.
Add ground beef and mix well.
Place in loaf pan and pat down.
Cover with foil and bake for 1 hour or until internal temperature reads 160°F.
Brush top with ketchup the last 10 minutes of baking and leave uncovered.
Allow to rest 10 minutes before cutting and serving.